The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 13, 2018
Filed:
Mar. 01, 2016
Applicants:
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
University of Guelph, Guelph, CA;
Inventors:
John W. Lawler, Swampscott, MA (US);
Mark Duquette, Southborough, MA (US);
James Petrik, Rockwood, CA;
Assignees:
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
University of Guelph, Guelph, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/78 (2006.01); C07K 16/00 (2006.01); A61K 47/68 (2017.01);
U.S. Cl.
CPC ...
C07K 14/78 (2013.01); A61K 47/68 (2017.08); C07K 16/00 (2013.01); C07K 2319/30 (2013.01);
Abstract
The invention features thrombospondin-1 (TSP-1) polypeptides (e.g., 3TSR-Fc fusion proteins), nucleic acid molecules encoding the TSP-1 polypeptides, and compositions thereof. The invention also features methods of making and using the TSP-1 polypeptides of the invention (e.g., using 3TSR-Fc fusion proteins to treat a subject having a disorder associated with pathological angiogenesis, e.g., cancer, e.g., epithelial ovarian cancer (EOC)).