The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 13, 2018
Filed:
Jun. 08, 2016
Arizona Board of Regents on Behalf of Arizona State University, Scottsdale, AZ (US);
Xuan Wang, Chandler, AZ (US);
Reed Cartwright, Chandler, AZ (US);
Christian Sievert, Tempe, AZ (US);
Taylor Loeffler, Peoria, AZ (US);
Lizbeth Nieves, Chandler, AZ (US);
Larry Panyon, Phoenix, AZ (US);
Chandler Morris, Tempe, AZ (US);
Arizona Board of Regents on behalf of Arizona State University, Scottsdale, AZ (US);
Abstract
The present invention relates to increasing xylose utilization in industrial microbe by inducing mutations in the regulator genes, crp and xylR. Thus the invention is directed to isolated nucleic acid sequences that encode mutations in the crp gene and the xylR gene and recombinant bacterium that express mutated CRP and XylR. In some embodiments, the mutation results in a point mutation at residue 142 of the CRP protein and/or at point mutation at residues 121, 182 and/or 363 of the XylR protein (based on the protein sequences in). The invention also includes methods of using the recombinant bacterium.