The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 13, 2018
Filed:
Jun. 19, 2015
Applicant:
Brandeis University, Waltham, MA (US);
Inventors:
Isaac J. Krauss, Waltham, MA (US);
Lizbeth K. Hedstrom, Newton, MA (US);
Iain S. MacPherson, Honolulu, HI (US);
Assignee:
Brandeis University, Waltham, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/10 (2006.01); C07H 15/22 (2006.01); A61K 39/21 (2006.01); A61K 47/48 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07H 21/04 (2013.01); A61K 39/21 (2013.01); A61K 47/4833 (2013.01); C07H 15/22 (2013.01); C12N 7/00 (2013.01); C12N 15/1048 (2013.01); C12N 15/1058 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/55511 (2013.01); A61K 2039/6068 (2013.01); A61K 2039/6081 (2013.01); A61K 2039/627 (2013.01);
Abstract
Described herein are oligosaccharide-oligonucleotide conjugates useful as vaccines against one or more human or veterinary therapeutic indications, and methods of synthesizing and identifying them. The conjugates may be identified using non-human antibodies as binding targets, thereby expanding the power and scope of the invention. Efficacious conjugates may be identified through an iterative screening process.