The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 13, 2018
Filed:
Apr. 27, 2017
Applicant:
University of Kansas, Lawrence, KS (US);
Inventors:
Thomas E. Prisinzano, Lawrence, KS (US);
Andrew P. Riley, Lawrence, KS (US);
Chad E. Groer, Lawrence, KS (US);
Assignee:
UNIVERSITY OF KANSAS, Lawrence, KS (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 407/14 (2006.01); C07D 407/04 (2006.01); C07D 405/14 (2006.01); C07D 417/14 (2006.01); C07D 401/14 (2006.01); C07D 411/14 (2006.01); C07D 413/14 (2006.01); G01N 33/50 (2006.01); G01N 33/94 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 407/04 (2013.01); C07D 407/14 (2013.01); C07D 411/14 (2013.01); C07D 413/14 (2013.01); G01N 33/5041 (2013.01); G01N 33/9486 (2013.01); G01N 2500/10 (2013.01);
Abstract
The present technology is directed to compounds, compositions, and methods related to non-morphinan-like mu opioid receptor agonists. Compounds of the present technology demonstrate remarkable potency and selectivity for the mu opioid receptor over the kappa opioid receptor, while also exhibiting a significant reduction (or, essentially, absence) of the negative side effects of many morphine-derived compounds.