The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 13, 2018

Filed:

Jun. 28, 2016
Applicants:

Sorin Crm Sas, Clamart, FR;

Universite DE Rennes 1, Rennes, FR;

Inserm-institut DE LA Recherche Medicale, Paris, FR;

Inventors:

Jean-Luc Bonnet, Massy, FR;

Alfredo Hernandez, Cesson Sévigné, FR;

Guy Carrault, Cesson-Sévigné, FR;

Hector Romero, Rennes, FR;

Virginie Le Rolle, Cesson-Sévigné, FR;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 1/36 (2006.01); G16H 50/20 (2018.01); A61N 1/365 (2006.01); A61N 1/05 (2006.01); G16H 50/50 (2018.01); A61B 5/00 (2006.01); A61N 1/372 (2006.01); G06F 19/00 (2018.01); A61B 5/0205 (2006.01);
U.S. Cl.
CPC ...
A61N 1/36139 (2013.01); A61N 1/0551 (2013.01); A61N 1/365 (2013.01); A61N 1/36053 (2013.01); A61N 1/36125 (2013.01); A61N 1/36146 (2013.01); A61N 1/37235 (2013.01); G06F 19/345 (2013.01); G16H 50/20 (2018.01); A61B 5/0205 (2013.01); A61B 5/4836 (2013.01); A61B 5/686 (2013.01); A61N 1/36114 (2013.01); A61N 1/36157 (2013.01); A61N 1/36175 (2013.01); A61N 1/36178 (2013.01); A61N 1/36521 (2013.01); A61N 1/36535 (2013.01); A61N 1/36542 (2013.01); A61N 1/36564 (2013.01); A61N 1/36571 (2013.01); A61N 1/36578 (2013.01); A61N 1/36585 (2013.01); A61N 1/36592 (2013.01); A61N 1/37247 (2013.01); G06F 19/3437 (2013.01); G16H 50/50 (2018.01);
Abstract

One system includes a stimulation device such as a vagus nerve stimulation lead, and a controller for controlling the stimulation device according to a set of stimulation parameters. A memory of the stimulation device contains a state transition model, and for each state defines a set of stimulation parameters and at least one expected response during the application of stimulation with the parameters. A matrix determines the transition rules between states based on physiological levels measured versus target levels. A state transition control unit determines, in an organized timely method, possible transitions between states according to the rules on physiological levels obtained in response to the implementation of the stimulation parameters of the current state, and a transition from a current state to a new state causes a corresponding change in the parameter set used for stimulation.


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