The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 06, 2018
Filed:
Jun. 25, 2011
Shai S. Shen-orr, Menlo Park, CA (US);
Atul J. Butte, Menlo Park, CA (US);
Mark M. Davis, Atherton, CA (US);
David Furman, San Francisco, CA (US);
Brian A. Kidd, Palo Alto, CA (US);
Shai S. Shen-Orr, Menlo Park, CA (US);
Atul J. Butte, Menlo Park, CA (US);
Mark M. Davis, Atherton, CA (US);
David Furman, San Francisco, CA (US);
Brian A. Kidd, Palo Alto, CA (US);
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Abstract
Embodiments of the present invention provide diagnostic markers of immunosenescence and methods of identifying individuals with impaired immune function based on a combination of such markers obtained from various analyzes, primarily from blood, testing immune function including the analysis of immune cell subset frequencies, gene expression, cytokine and chemokine levels, and signaling responses to stimulation with cytokines ('cytokine response'). Particular combinations of markers can predict with high accuracy whether an individual will respond to active vaccination and become protected against recurring diseases.