The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 06, 2018
Filed:
Aug. 17, 2007
Applicants:
Germaine Fuh, Pacifica, CA (US);
Jenny M. Bostrom, Moss Beach, CA (US);
Inventors:
Germaine Fuh, Pacifica, CA (US);
Jenny M. Bostrom, Moss Beach, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/32 (2006.01); C07K 16/22 (2006.01); C07K 16/28 (2006.01); C07K 16/42 (2006.01); C07K 16/46 (2006.01);
U.S. Cl.
CPC ...
C07K 16/32 (2013.01); C07K 16/22 (2013.01); C07K 16/2878 (2013.01); C07K 16/4283 (2013.01); C07K 16/468 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01);
Abstract
The invention provides multispecific antibodies and methods of making and using such antibodies. In general, the multispecific antibodies are made by methods involving the steps of altering the nucleic acid sequence encoding the light chain variable domain (V) of an antibody that binds a first epitope, and selecting a multispecific antibody capable of binding the first and a second epitope.