The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 06, 2018
Filed:
Dec. 04, 2015
Astrazeneca Ab, Sodertalje, SE;
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
David W. Christianson, Media, PA (US);
Bruce Edward Tomczuk, Collegeville, PA (US);
Richard Scott Pottorf, Belle Mead, NJ (US);
Andrew Vargha Colasanti, Scotch Plains, NJ (US);
Gary Lee Olson, Mountainside, NJ (US);
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
AstraZeneca AB, Sodertalje, SE;
Abstract
The present invention is directed to arginase inhibitor compounds of formula IA or formula IB: or a pharmaceutically acceptable salt thereof, compositions containing these compounds, and methods of their use for the treatment and diagnosis of conditions characterized by upregulation of arginase, abnormally high arginase activity, or by abnormally low nitric oxide synthase activity.