The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 06, 2018

Filed:

Apr. 19, 2018
Applicants:

Bioventures, Llc, Little Rock, AR (US);

The Regents of the University of Colorado, a Body Corporate, Denver, CO (US);

Inventors:

Venumadhav Janganati, Little Rock, AR (US);

Peter Crooks, Little Rock, AR (US);

Narsimha Reddy Penthala, Little Rock, AR (US);

Craig Jordan, Denver, CO (US);

Shobanbabu Bommagani, Little Rock, AR (US);

Jessica Ponder, Denver, CO (US);

Assignees:

BioVentures, LLC, Little Rock, AZ (US);

The Regents of the University of Colorado, Denver, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 519/00 (2006.01); C07F 7/18 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); C07F 7/1852 (2013.01);
Abstract

The present disclosure provides dimers of melampomagnolide B (MMB), including carbamate, carbonate, succinic amide, ester and carboxamide dimers of MMB. These derivatives are useful for treating cancer in humans, in particular in treating leukemia, including acute myelogenous leukemia (AML).


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