The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 06, 2018
Filed:
Oct. 30, 2015
Bayer Pharma Aktiengesellschaft, Berlin, DE;
Manuel Ellermann, Berlin, DE;
Gaelle Valot, Wuppertal, DE;
Yolanda Cancho Grande, Leverkusen, DE;
Jorma Haßfeld, Düsseldorf, DE;
Tom Kinzel, Beijing, CN;
Johannes Köbberling, Neuss, DE;
Kristin Beyer, Düsseldorf, DE;
Susanne Röhrig, Hilden, DE;
Michael Sperzel, Kierspe, DE;
Jan Stampfuß, Düsseldorf, DE;
Imke Meyer, Haan, DE;
Maria Köllnberger, Velbert, DE;
Nils Burkhardt, Velbert, DE;
Karl-Heinz Schlemmer, Wuppertal, DE;
Christian Stegmann, Berlin, DE;
Joachim Schuhmacher, Kirchseeon, DE;
Matthias Werner, Feldkirchen-Westerham, DE;
Jörg Heiermann, Wesel, DE;
Willem Jan Hengeveld, Arnhem, NL;
BAYER PHARMA AKTIENGESELLSCHAFT, Berlin, DE;
Abstract
The present application relates to novel substituted piperidinylpyrazolopyrimidinones, to processes for their preparation, the compounds for use alone or in combinations in a method for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of acute and recurrent bleeding in patients with or without underlying hereditary or acquired hemostatic disorders, wherein the bleeding is associated with a disease or medical intervention selected from the group consisting of heavy menstrual bleeding, postpartum hemorrhage, hemorrhagic shock, hemorrhagic cystitis, gastrointestinal hemorrhage, trauma, surgery, transplantation, stroke, liver diseases, hereditary angioedema, nosebleed, and synovitis and cartilage damage following hemarthrosis.