The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 06, 2018
Filed:
Apr. 25, 2017
Abbvie S.à.r.l., Luxembourg, LU;
Galapagos NV, Mechelen, BE;
Robert J. Altenbach, Chicago, IL (US);
Andrew Bogdan, Evanston, IL (US);
Vincent Chan, Evanston, IL (US);
Timothy A. Grieme, Chicago, IL (US);
John R. Koenig, Chicago, IL (US);
Philip R. Kym, Libertyville, IL (US);
Bo Liu, Waukegan, IL (US);
Karine Fabienne Malagu, Saffron Walden, GB;
Sachin V. Patel, Round Lake, IL (US);
Marc Scanio, Libertyville, IL (US);
Xenia B. Searle, Grayslake, IL (US);
Shashank Shekhar, Vernon Hills, IL (US);
Xueqing Wang, Northbrook, IL (US);
Ming C. Yeung, Grayslake, IL (US);
AbbVie S.á.r.l., Luxembourg, LU;
Galapagos NV, Mechelen, BE;
Abstract
The present invention provides for compounds of formula (I) wherein R, m, Z, G, R, and Rhave any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions mediated and modulated by CFTR, including cystic fibrosis, Sjögren's syndrome, pancreatic insufficiency, chronic obstructive lung disease, and chronic obstructive airway disease. Also provided are pharmaceutical compositions comprised of one or more compounds of formula (I).