The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 06, 2018
Filed:
Jun. 03, 2016
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Robert J. Davies, Arlington, MA (US);
Jingrong Cao, Newton, MA (US);
Meghan Elise Cockerill, Boston, MA (US);
Philip Noel Collier, Hingham, MA (US);
Elisabeth Doyle, Worcester, MA (US);
James Daniel Frantz, Belmont, MA (US);
Huai Gao, Arlington, MA (US);
Brian Anthony Goldman, Brookline, MA (US);
Ronald Lee Grey, Jr., Mansfield, MA (US);
Anne-Laure Grillot, Milton, MA (US);
Wenxin Gu, Concord, MA (US);
James A. Henderson, Weston, MA (US);
Raul Eduardo Krauss Irarrazaval, Chestnut Hill, MA (US);
Adrianne Lynn Kolpak, Watertown, MA (US);
Yusheng Liao, Lexington, MA (US);
Sanjay Shivayogi Magavi, Cambridge, MA (US);
David Messersmith, Somerville, MA (US);
Albert Charles Pierce, Cambridge, MA (US);
Emanuele Perola, Brookline, MA (US);
Elizabeth Jin-Sun Ryu, Newton, MA (US);
Joshua Syken, Jamaica Plain, MA (US);
Jian Wang, Newton, MA (US);
Michael Paul DeNinno, Gales Ferry, CT (US);
Francois Maltais, Tewksbury, MA (US);
VERTEX PHARMACEUTICALS INCORPORATED, Boston, MA (US);
Abstract
The invention relates to triazole compounds of formula I and I' or pharmaceutically acceptable salts thereof, useful as modulators of demyelinating diseases: The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention, methods of using the compositions and kits thereof in the treatment of various demyelinating and neurodegenerative diseases, including multiple sclerosis.