The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 06, 2018

Filed:

Oct. 09, 2015
Applicant:

Illumina, Inc., San Diego, CA (US);

Inventors:

Eric Hans Vermaas, San Diego, CA (US);

Matthew Hage, San Diego, CA (US);

Assignee:

ILLUMINA, INC., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D 35/00 (2006.01); G01N 1/18 (2006.01); G01N 1/00 (2006.01); B01L 3/00 (2006.01); B01D 17/02 (2006.01); B01D 17/00 (2006.01); B01D 63/08 (2006.01); B01D 69/02 (2006.01); B01D 71/36 (2006.01); C12Q 1/6806 (2018.01);
U.S. Cl.
CPC ...
B01L 3/502784 (2013.01); B01D 17/0202 (2013.01); B01D 17/0214 (2013.01); B01D 17/085 (2013.01); B01D 63/088 (2013.01); B01D 69/02 (2013.01); B01D 71/36 (2013.01); B01L 3/50255 (2013.01); B01D 2325/38 (2013.01); B01L 2200/0673 (2013.01); B01L 2200/10 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/12 (2013.01); B01L 2300/165 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0409 (2013.01); C12Q 1/6806 (2013.01);
Abstract

Method that includes providing a phase-separation device having a porous membrane with a filter surface. The filter surface has a non-planar contour that forms a receiving cavity. The method also includes providing a liquid mixture into the receiving cavity of the porous membrane. The liquid mixture includes a polar liquid and a non-polar liquid that are immiscible with respect to each other. The filter surface along the receiving cavity has a surface energy that impedes flow of the polar liquid through the filter surface and permit flow of the non-polar liquid into the porous membrane. The method also includes permitting the non-polar liquid to flow into the porous membrane. The polar liquid forms a droplet within the receiving cavity as the non-polar liquid flows into the porous membrane.


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