The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 06, 2018

Filed:

Mar. 30, 2015
Applicants:

The University of Chicago, Chicago, IL (US);

The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);

Inventors:

Wenbin Lin, Chicago, IL (US);

Joseph M. Falkowski, Annandale, NJ (US);

Takahiro Sawano, Chicago, IL (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01J 31/16 (2006.01); C07C 45/69 (2006.01); C07C 231/02 (2006.01); B01J 31/18 (2006.01); B01J 31/24 (2006.01); C07C 227/04 (2006.01); C07C 29/44 (2006.01); C07C 41/09 (2006.01); C07C 67/303 (2006.01); C07D 307/93 (2006.01);
U.S. Cl.
CPC ...
B01J 31/1691 (2013.01); B01J 31/1805 (2013.01); B01J 31/2409 (2013.01); B01J 31/2447 (2013.01); C07C 29/44 (2013.01); C07C 41/09 (2013.01); C07C 45/69 (2013.01); C07C 67/303 (2013.01); C07C 227/04 (2013.01); C07C 231/02 (2013.01); C07D 307/93 (2013.01); B01J 2531/0263 (2013.01); B01J 2531/0266 (2013.01); B01J 2531/822 (2013.01); C07C 2102/44 (2013.01);
Abstract

Metal-organic framework (MOFs) compositions based on chiral phosphine-, chiral oxazoline-, chiral pyridine-, and chiral diene-derived organic bridging ligands were synthesized and then post-synthetically metalated with metal precursors such as Ru and Rh complexes. The metal complexes could also be directly incorporated into the MOFs. The MOFs provide a versatile family of recyclable and reusable single-site solid catalysts for catalyzing a variety of asymmetric organic transformations, including the addition of arylboronic acids to α,β-unsaturated ketones and alkimines, the hydrogenation of substituted alkene and carbonyl compounds, and cyclization reactions. The solid catalysts can also be integrated into a flow reactor or a supercritical fluid reactor.


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