The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 06, 2018

Filed:

Nov. 03, 2014
Applicant:

Arrow International, Inc., Wayne, PA (US);

Inventors:

Jun Li, Brookline, MA (US);

Zheng Zhang, Cambridge, MA (US);

Chad C. Huval, Somerville, MA (US);

Michael A. Bouchard, Wyomissing, PA (US);

Christopher R. Loose, Cambridge, MA (US);

Arthur J. Coury, Boston, MA (US);

Assignee:

ARROW INTERNATIONAL, INC., Wayne, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 33/00 (2006.01); A61L 29/06 (2006.01); A61L 29/08 (2006.01); C08F 291/00 (2006.01); C08J 7/16 (2006.01); C08J 7/18 (2006.01); C08F 255/02 (2006.01); C08G 18/83 (2006.01); C08G 64/42 (2006.01); C08G 77/38 (2006.01);
U.S. Cl.
CPC ...
A61L 33/0088 (2013.01); A61L 29/06 (2013.01); A61L 29/085 (2013.01); C08F 255/02 (2013.01); C08F 291/00 (2013.01); C08G 18/836 (2013.01); C08G 64/42 (2013.01); C08G 77/38 (2013.01); C08J 7/16 (2013.01); C08J 7/18 (2013.01); C08J 2323/12 (2013.01); C08J 2369/00 (2013.01); C08J 2383/04 (2013.01); C08J 2433/14 (2013.01); Y10T 428/24355 (2015.01); Y10T 428/265 (2015.01); Y10T 442/30 (2015.04); Y10T 442/60 (2015.04);
Abstract

A method for preparing and resulting articles of manufacture comprising a substrate having a surface, a bulk beneath the surface, and a grafted polymer layer on the substrate surface, the substrate surface and the grafted polymer layer, in combination, constituting a modified surface having a fibrinogen adsorption of less than about 125 ng/cmin a fibrinogen binding assay in which the modified surface is incubated for 60 minutes at 37° C. in 70 μg/mL fibrinogen derived from human plasma containing 1.4 μg/mL I-125 radiolabeled fibrinogen.


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