The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 06, 2018
Filed:
Oct. 13, 2017
The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);
Vanderbilt University, Nashville, TN (US);
Aravinda M. de Silva, Chapel Hill, NC (US);
A. Ruklanthi de Alwis, Dehiwala, LK;
Wahala M. P. B. Wahala, Carmel, IN (US);
Ralph S. Baric, Haw River, NC (US);
William B. Messer, Portland, OR (US);
James E. Crowe, Jr., Nashville, TN (US);
Scott A. Smith, Nashville, TN (US);
The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Vanderbilt University, Nashville, TN (US);
Abstract
The present invention provides compositions and methods of use comprising a chimeric dengue virus E glycoprotein comprising a dengue virus E glycoprotein backbone, which comprises amino acid substitutions that introduce a dengue virus E glycoprotein domain I and domain II hinge region from a dengue virus serotype that is different from the dengue virus serotype of the dengue virus E glycoprotein backbone.