The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 06, 2018
Filed:
Dec. 28, 2016
Applicants:
Ugur Sahin, Mainz, DE;
Ozlem Tureci, Mainz, DE;
Petra Simon, Mainz, DE;
Tana Omokoko, Mainz, DE;
Inventors:
Assignees:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0783 (2010.01); A61K 39/00 (2006.01); C12N 9/16 (2006.01); C07K 14/725 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); C07K 14/7051 (2013.01); C12N 5/0636 (2013.01); C12N 9/16 (2013.01); C12Y 301/03048 (2013.01); G01N 33/5017 (2013.01); A61K 2039/57 (2013.01); C12N 2510/00 (2013.01); G01N 2333/916 (2013.01);
Abstract
The present invention relates to efficient methods for providing antigen-specific lymphoid cells. These lymphoid cells may be used to provide antigen specific T cell receptors having a defined MHC restriction and to identify immunologically relevant T cell epitopes. Furthermore, the present invention relates to antigen-specific T cell receptors and T cell epitopes and their use in immunotherapy.