The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 30, 2018

Filed:

Dec. 18, 2017
Applicant:

Biothera, Inc., Eagan, MN (US);

Inventors:

Nandita Bose, Plymouth, MN (US);

Mary A. Antonysamy, Woodbury, MN (US);

Keith B. Gorden, Woodbury, MN (US);

Richard Walsh, Lino Lakes, MN (US);

Michael E. Danielson, St. Paul, MN (US);

Peter Maimonis, Westwood, MA (US);

Assignee:

Biothera, Inc., Eagan, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/68 (2006.01); C07K 16/14 (2006.01); G01N 33/569 (2006.01); A61K 39/00 (2006.01); C07K 16/16 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6854 (2013.01); A61K 39/0002 (2013.01); C07K 16/14 (2013.01); G01N 33/53 (2013.01); G01N 33/56961 (2013.01); C07K 16/16 (2013.01); G01N 2400/24 (2013.01); G01N 2800/24 (2013.01);
Abstract

This disclosure provides, in one aspect, a method for analyzing a sample from a subject for a biomarker that is indicative of the subject's immune response to β-glucan. Generally, the method includes obtaining a biological sample from a subject, analyzing the sample for a biomarker anti-β-glucan antibody compared to a reference standard, computing a Relative Antibody Unit (RAU) value for anti-β-glucan antibody in the sample, and identifying the subject as biomarker positive if the RAU value is greater than a predetermined RAU value for the biomarker anti-β-glucan antibody.


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