The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 30, 2018

Filed:

Apr. 21, 2015
Applicants:

Inserm (Institut National DE LA Santé ET DE LA Recherche Médicale), Paris, FR;

Institut Curie, Paris, FR;

Universite Paris Descartes, Paris, FR;

Inventors:

Eliane Piaggio, Paris, FR;

Louis Perol, Paris, FR;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/10 (2006.01); G01N 33/564 (2006.01); C07K 14/47 (2006.01); G01N 33/00 (2006.01); C07K 14/55 (2006.01); C07K 16/24 (2006.01);
U.S. Cl.
CPC ...
G01N 33/564 (2013.01); C07K 14/4713 (2013.01); C07K 14/55 (2013.01); C07K 16/246 (2013.01); G01N 33/00 (2013.01); A61K 38/00 (2013.01); C07K 2317/14 (2013.01); G01N 2333/55 (2013.01); G01N 2800/24 (2013.01); G01N 2800/50 (2013.01); G01N 2800/52 (2013.01);
Abstract

An in vitro method for determining whether a patient has, or is at risk of having or developing an autoimmune disease or for assessing the severity or predicting the outcome of an autoimmune disease, comprising a step of detecting or quantifying in a biological sample obtained from said patient an immune anti-IL2 response, peptides specifically recognized by anti-IL2 antibodies or IL-2-specific T cells of T1D, systemic lupus erythematosus, rheumatoid arthritis, Sjögren's syndrome and autoimmune polymyositis patients, and pharmaceutical compositions.


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