The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 30, 2018
Filed:
Mar. 18, 2015
Applicant:
Carmel-haifa University Economic Corp. Ltd, Haifa, IL;
Inventors:
Kobi Rosenblum, Haifa, IL;
Akiva Rappaport, Haifa, IL;
Assignee:
Carmel-Haifa University Economic Corp. Ltd., Haifa, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 31/7105 (2006.01); A61K 31/713 (2006.01); A61K 31/165 (2006.01); A61K 31/404 (2006.01); A61K 31/4045 (2006.01); A61K 31/4375 (2006.01); A61K 31/455 (2006.01); A61K 31/7064 (2006.01); A61K 31/255 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1137 (2013.01); A61K 31/165 (2013.01); A61K 31/255 (2013.01); A61K 31/404 (2013.01); A61K 31/4045 (2013.01); A61K 31/4375 (2013.01); A61K 31/455 (2013.01); A61K 31/7064 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); C12Y 106/05005 (2013.01); C12N 2310/14 (2013.01); C12N 2310/531 (2013.01);
Abstract
An active agent capable of reducing quinone reductase 2 activity, for use in improvement of cognition in a subject is provided. Such an active agent may be a nucleic acid molecule that reduces the gene expression level of quinone reductase 2 or an inhibitor of quinone reductase 2 activity. A vector comprising a nucleic acid molecule that reduces the gene expression level of quinone reductase 2 and a pharmaceutical composition comprising an active agent capable of reducing quinone reductase 2 activity or said vector are provided as well.