The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 30, 2018

Filed:

Dec. 17, 2014
Applicant:

Memorial Sloan-kettering Cancer Center, New York, NY (US);

Inventors:

Jeffrey H. Rothman, Greenwich, CT (US);

Gary K. Schwartz, Briarcliff Manor, NY (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C07K 14/00 (2006.01); C12Q 1/6886 (2018.01); G01N 33/574 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1135 (2013.01); C07K 14/003 (2013.01); C12Q 1/6886 (2013.01); G01N 33/5748 (2013.01); A61K 38/00 (2013.01); C12N 2310/3181 (2013.01); C12N 2310/3513 (2013.01); C12N 2310/3515 (2013.01); C12N 2310/531 (2013.01); C12N 2320/30 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01); G01N 2500/10 (2013.01);
Abstract

The present invention provides compositions and methods for treating cancer with peptide nucleic acid agents. In some embodiments, the present invention provides methods and compositions relating to peptide nucleic acid agents that target oncogenes. For example, the present invention provides compositions, including pharmaceutical compositions, comprising agents specific for BRAF V600E inhibition, or fragments or characteristic portions thereof. The present invention further provides various therapeutic and/or diagnostic methods of using BRAF V600E specific peptide nucleic acid agents and/or compositions.


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