The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 30, 2018
Filed:
Apr. 08, 2014
Applicant:
Academisch Ziekenhuis Leiden, Leiden, NL;
Inventors:
Judith Christina Theodora Van Deutekom, Dordrecht, NL;
Garrit-Jan B. van Ommen, Amserdam, NL;
Annemieke Aartsma-Rus, Hoofddorp, NL;
Johannes Theodorus den Dunnen, Rotterdam, NL;
Assignee:
ACADEMISCH ZIEKENHUIS LEIDEN, Leiden, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 15/113 (2010.01); C07H 21/02 (2006.01); C12Q 1/6883 (2018.01); G01N 33/68 (2006.01); C12N 15/85 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 48/0016 (2013.01); C07H 21/02 (2013.01); C12N 15/85 (2013.01); C12Q 1/6883 (2013.01); G01N 33/6887 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); C12N 2310/11 (2013.01); C12N 2310/111 (2013.01); C12N 2310/31 (2013.01); C12N 2310/314 (2013.01); C12N 2310/315 (2013.01); C12N 2310/3181 (2013.01); C12N 2310/321 (2013.01); C12N 2310/3231 (2013.01); C12N 2310/3233 (2013.01); C12N 2310/346 (2013.01); C12N 2320/30 (2013.01); C12N 2320/33 (2013.01);
Abstract
The invention relates to oligonucleotides for inducing skipping of exon 53 of the dystrophin gene. The invention also relates to methods of inducing exon 53 skipping using the oligonucleotides.