The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 30, 2018
Filed:
Jul. 01, 2015
Applicant:
Xavier University of Louisiana, New Orleans, LA (US);
Inventors:
Guangdi Wang, New Orleans, LA (US);
Qiu Zhong, Metairie, LA (US);
Shilong Zheng, New Orleans, LA (US);
Assignee:
XAVIER UNIVERSITY, New Orleans, LA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07J 31/00 (2006.01); C07F 5/02 (2006.01); C07F 5/04 (2006.01); C07J 51/00 (2006.01); C07H 23/00 (2006.01);
U.S. Cl.
CPC ...
C07F 5/025 (2013.01); C07F 5/027 (2013.01); C07F 5/04 (2013.01); C07H 23/00 (2013.01); C07J 31/006 (2013.01); C07J 51/00 (2013.01);
Abstract
Boron-based prodrugs of phenol- or aromatic hydroxyl group-containing therapeutic molecules ('original drugs'), uses thereof, and methods of making the same, are provided for achieving, for example, improved bioavailability, prolonged retention (e.g., in a circulatory system) and, in particular, significantly lowered therapeutically effective dosage in order to reduce adverse effects while maintaining the desired therapeutic effects of the original drugs.