logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10112935 B1

PDFFull Text
Expired
Date of Patent:
Oct. 30, 2018

Filed:

Feb. 26, 2016

Indazolyl thiadiazolamines and related compounds for inhibition of rho-associated protein kinase and the treatment of disease

Applicant:

Lycera Corporation, Ann Arbor, MI (US);

Inventors:

Thomas Daniel Aicher, Ann Arbor, MI (US);

Fernando Padilla, Ann Arbor, MI (US);

Peter L. Toogood, Ann Arbor, MI (US);

Shoujun Chen, Ann Arbor, MI (US);

Assignee:

Lycera Corporation, Ann Arbor, MI (US);

Attorney:

Dechert LLP

Primary Examiner:

Rebecca L Anderson

Assistant Examiner:

Karen Cheng

Int. Cl.
CPC ...
C07D 417/12 (2006.01); A61K 31/416 (2006.01); A61K 31/433 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 498/04 (2006.01); C07D 513/04 (2006.01); A61P 11/00 (2006.01);
U.S. Cl.
CPC ...
C07D 417/12 (2013.01); A61K 31/416 (2013.01); A61K 31/433 (2013.01); A61P 11/00 (2018.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 498/04 (2013.01); C07D 513/04 (2013.01);
Abstract

The invention provides indazolyl thiadiazolamines and related compounds, pharmaceutical compositions, methods of inhibiting Rho-associated protein kinase, and methods of treating inflammatory disorders, immune disorders, fibrotic disorders, and other medical disorders using such compounds. An exemplary indazolyl thiadiazolamine compound is an N-(5-[5-[(1H4ndazol-5-yl)amino]-1,3,4-thiadiazol-2-yl]pyridin-3-yl)acetamide compound.

Find Patent Forward Citations

Aicher, Thomas. (2018). Indazolyl thiadiazolamines and related compounds for inhibition of rho-associated protein kinase and the treatment of disease (U.S. Patent No. 10112935). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10112935

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…