The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 30, 2018
Filed:
Jul. 18, 2014
Applicant:
Baylor College of Medicine, Houston, TX (US);
Inventors:
David J. Tweardy, Houston, TX (US);
Moses M. Kasembeli, Houston, TX (US);
Marvin X. Xu, Shanghai, CN;
Sandeep K. Agarwal, Houston, TX (US);
Mesias Pedroza, Houston, TX (US);
Assignee:
BAYLOR COLLEGE OF MEDICINE, Houston, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/12 (2006.01); A61K 31/18 (2006.01); C07C 317/28 (2006.01); C07C 317/30 (2006.01); C07C 317/32 (2006.01); C07D 213/71 (2006.01); C07D 215/06 (2006.01); C07D 231/18 (2006.01); C07D 239/60 (2006.01); C07D 261/10 (2006.01); C07D 333/34 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); A61K 31/343 (2006.01); A61K 31/39 (2006.01); A61K 31/4196 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 417/12 (2013.01); A61K 31/18 (2013.01); A61K 31/343 (2013.01); A61K 31/39 (2013.01); A61K 31/4196 (2013.01); A61K 45/06 (2013.01); C07C 317/28 (2013.01); C07C 317/30 (2013.01); C07C 317/32 (2013.01); C07D 213/71 (2013.01); C07D 215/06 (2013.01); C07D 231/18 (2013.01); C07D 239/60 (2013.01); C07D 261/10 (2013.01); C07D 333/34 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01);
Abstract
Embodiments of the invention include methods of treating, preventing, and/or reducing the risk of fibrosis in an individual in need thereof. In some embodiments, particular small molecules are employed for treatment, prevention, and/or reduction of the risk of fibrosis. In at least particular cases, the small molecules are inhibitors of STAT3.