The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 30, 2018
Filed:
Nov. 04, 2016
Heptares Therapeutics Limited, Welwyn Garden, Hertfordshire, GB;
Miles Stuart Congreve, Welwyn Garden, GB;
Stephen Philippe Andrews, Melbourn, GB;
Jonathan Stephen Mason, Walmer, GB;
Christine Mary Richardson, Saffron Walden, GB;
Giles Albert Brown, Cambridge, GB;
Heptares Therapeutics Limited, Welwyn Garden, GB;
Abstract
According to the invention there is provided a compound of formula A1 which may be useful in the treatment of a condition or disorder ameliorated by the inhibition of the A-Aor, particularly, the Areceptor wherein the compound of formula A1 has the structure, wherein, A represents Cyor Het; Cyrepresents a 5- to 14-membered aromatic, fully saturated or partially unsaturated carbocylic ring system comprising one, two or three rings, which Cygroup is optionally substituted by one or more Rsubstituents; Hetrepresents a 5- to 14-membered heterocyclic group that may be aromatic, fully saturated or partially unsaturated, and which contains one or more heteroatoms selected from O, S and N, which heterocyclic group may comprise one, two or three rings and which HetA group is optionally substituted by one or more R4b substituents; B represents a Cyor Het; Cyrepresents a 3- to 10-membered aromatic, fully saturated or partially unsaturated carbocyclic ring system comprising one or two rings, which Cygroup is optionally substituted by one or more Rsubstituents; Hetrepresents a 3- to 10-membered heterocyclic group that may be aromatic, fully saturated or partially unsaturated, and which contains one or more heteroatoms selected from O, S and N, which heterocyclic group may comprise one or two rings and which Hetgroup is optionally substituted by one or more Rsubstituents.