The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 30, 2018

Filed:

Dec. 03, 2014
Applicant:

Hookipa Biotech Gmbh, Vienna, AT;

Inventors:

Klaus Orlinger, Vienna, AT;

Karen Lingnau, Vienna, AT;

Thomas Monath, Harvard, MA (US);

Farshad Guirakhoo, Melrose, MA (US);

Gerhard Fuhrmann, Vienna, AT;

Katherine Cohen, Vienna, AT;

Vera Baumgartl-Strasser, Purkersdorf, AT;

Andreas Aspöck, Vienna, AT;

Manuela Kainer, Neulengback, AT;

Bernhard Brim, Mauerback, AT;

Bettina Kiefmann, Vienna, AT;

Elizabeth Watson, Vienna, AT;

Mario Aistleithner, Vienna, AT;

Katharina Bayer, Mistelbach, AT;

Elsa Mühlbacher, Vienna, AT;

Assignee:

Hookipa Biotech GmbH, Vienna, AT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/245 (2006.01); C07K 16/10 (2006.01); C12N 7/00 (2006.01); C07K 14/005 (2006.01); A61K 39/12 (2006.01); C12N 15/86 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/245 (2013.01); A61K 39/12 (2013.01); C07K 14/005 (2013.01); C07K 16/10 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); A61K 2039/5254 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/54 (2013.01); A61K 2039/55566 (2013.01); C07K 2319/00 (2013.01); C12N 2710/16134 (2013.01); C12N 2760/10021 (2013.01); C12N 2760/10043 (2013.01); C12N 2840/20 (2013.01); C12N 2840/206 (2013.01);
Abstract

Provided herein are genetically modified arenaviral vectors suitable as vaccines for prevention and treatment of cytomegalovirus infections and reactivation. Also provided herein are pharmaceutical compositions and methods for the treatment of cytomegalovirus infections and reactivation. Specifically, provided herein are pharmaceutical compositions, vaccines, and methods of treating cytomegalovirus infections and reactivation.


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