The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 30, 2018
Filed:
Sep. 14, 2016
Applicant:
Saint Louis University, St. Louis, MO (US);
Inventor:
Rajeev Aurora, Wildwood, MO (US);
Assignee:
Saint Louis University, St. Louis, MO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
A61K 38/177 (2013.01);
Abstract
Systems and methods for treating osteogenesis imperfecta using FoxP3+ CD8 T-cells (Tc). Osteoclasts are induced to produce FoxP3+ CD8 T-cells (Tc) through introduction of a low-dose of a RANK agonist such as RANKL. The RANKL was found to best work when provided in accordance with a schedule resulting in a pulsed administration.