The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 30, 2018
Filed:
Jun. 19, 2015
Inserm (Institut National DE LA Sante ET DE LA Recherche Medicale), Paris, FR;
Centre National DE LA Recherche Scientifique (Cnrs), Paris, FR;
Universite Paris Descartes, Paris, FR;
Fondation Imagine, Paris, FR;
Universite Paris Diderot—paris 7, Paris, FR;
Universite Paris-sud, Orsay, FR;
Assistance Publique-hopitaux DE Paris (Aphp), Paris, FR;
Ivan Cruz-Moura, Paris, FR;
Olivier Hermine, Paris, FR;
Etienne Paubelle, Paris, FR;
Michael Dussiot, Paris, FR;
Thiago Trovati Maciel, Paris, FR;
Florence Zylbersztejn, Paris, FR;
Institut National de la Sante et de la Recherche Medicale (INSERM), Paris, FR;
Centre National de la Recherche Scientifique (C.N.R.S.), Paris, FR;
Universite Paris Descartes, Paris, FR;
Foundation Imagine, Paris, FR;
Universite Paris Diderot—Paris 7, Paris, FR;
Universite Paris—Sud, Orsay, FR;
Assistance Publique-Hopitaux de Paris (APHP), Paris, FR;
Abstract
The present invention concerns a combination of (i) a DNA methylation inhibitor, and (ii) a Vitamin D receptor agonist, for simultaneous or sequential use in the treatment of a drug resistant cancer and/or in prevention of tumor relapse in a patient suffering from cancer. The present invention also relates to a combination of (i) a DNA methylation inhibitor, and (ii) a Vitamin D receptor agonist, for increasing, restoring or enhancing sensitivity of a patient suffering from cancer to a chemotherapeutic drug in a patient suffering from cancer.