The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 30, 2018

Filed:

Apr. 25, 2017
Applicant:

Curis, Inc., Lexington, MA (US);

Inventors:

Xiong Cai, Bedford, MA (US);

Haixiao Zhai, Bedford, MA (US);

Chengjung Lai, Belmont, MA (US);

Chenggeng Qian, Wayland, MA (US);

Assignee:

Curis, Inc., Lexington, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/30 (2006.01); A61K 31/4365 (2006.01); C07D 495/04 (2006.01); A61K 31/166 (2006.01); C07D 241/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4365 (2013.01); A61K 31/166 (2013.01); C07D 213/30 (2013.01); C07D 241/10 (2013.01); C07D 495/04 (2013.01);
Abstract

The invention provides a compound of Formula I, Pharmaceutical compositions comprising such compounds and the use of such compounds in the treatment of phosphoinositide 3-kinase related diseases and disorders such as cancer. The instant application further relates to the treatment of histone deacetylase related disorders and diseases related to both histone deacetylase and phosphoinositide 3-kinase.


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