The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 23, 2018

Filed:

Dec. 31, 2010
Applicants:

James P. Reilly, Bloomington, IN (US);

Liangyi Zhang, South San Francisco, CA (US);

Inventors:

James P. Reilly, Bloomington, IN (US);

Liangyi Zhang, South San Francisco, CA (US);

Assignee:

The Trustees of Indiana University, Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/62 (2006.01); G01N 33/68 (2006.01); G06F 19/18 (2011.01); G06F 19/24 (2011.01);
U.S. Cl.
CPC ...
G01N 33/6818 (2013.01); G01N 33/6848 (2013.01); G06F 19/18 (2013.01); G06F 19/24 (2013.01);
Abstract

Methods of identifying polypeptides have been developed using a de novo sequencing technique. Methods use photodissociation and low-energy fragmentation and the spectra of peptide ions obtained therefrom, such as obtained by post-source decay (PSD), have been developed. The methods include photodissociation and the spectra therefrom obtainable from treating ions with predetermined wavelengths of radiation in the vacuum ultraviolet range of the electromagnetic spectrum. The confidence of amino acid assignments based on x-type ions is evaluated by observing complementary y-, v- and w-type ions that provide additional constraints to sequence identification.


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