The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 23, 2018

Filed:

May. 21, 2015
Applicants:

Joseph R. Lakowicz, Ellicott City, MD (US);

Ramachandram Badugu, Ellicott City, MD (US);

Inventors:

Joseph R. Lakowicz, Ellicott City, MD (US);

Ramachandram Badugu, Ellicott City, MD (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/551 (2006.01); G01N 33/543 (2006.01); G01N 33/552 (2006.01); G02B 1/00 (2006.01); G01N 21/64 (2006.01); G02B 5/00 (2006.01); G01N 21/77 (2006.01); G02B 6/122 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54373 (2013.01); G01N 21/6445 (2013.01); G01N 21/7703 (2013.01); G01N 33/551 (2013.01); G01N 33/552 (2013.01); G01N 33/58 (2013.01); G02B 1/005 (2013.01); G02B 5/008 (2013.01); G02B 6/1225 (2013.01); G01N 2021/7786 (2013.01);
Abstract

Techniques for enhanced fluorescence include a functionalized substrate for a target optical frequency comprising a one dimensional photonic crystal that is functionalized with a bioactive target molecule that has an affinity for a particular analytic. The one dimensional photonic crystal includes a plurality of dielectric layers including a plurality of high index of refraction layers alternating with a plurality of low index of refraction layers. The thickness of each layer is within a factor of four of a wavelength of the optical frequency in the layer. For emissions from a fluorophore bound to the target molecule and excited by incident light, there is an emission intensity maximum centered at an angle independent of the direction of the incident light.


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