The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 23, 2018
Filed:
Mar. 25, 2009
Stig Hansen, Kensington, CA (US);
Daniel Erlanson, San Francisco, CA (US);
Mark Cancilla, San Mateo, CA (US);
Stig Hansen, Kensington, CA (US);
Daniel Erlanson, San Francisco, CA (US);
Mark Cancilla, San Mateo, CA (US);
SUNESIS PHARMACEUTICALS, INC., South San Francisco, CA (US);
Abstract
Herein is described a method to rapidly screen a large chemical space for a compound that binds to a target protein through an iterative fragment assembly approach that can be performed at low reagent cost and without requiring purification of the assembled product. The method employs a library of test ligands each of which comprise a 'bait' molecule, which is known from prior art or prior screening to have some intrinsic affinity for the target protein, and a test moiety.