The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 23, 2018
Filed:
Feb. 13, 2014
Applicant:
The J. David Gladstone Institutes, San Francisco, CA (US);
Inventor:
Leor S. Weinberger, San Francisco, CA (US);
Assignee:
The J. David Gladstone Institutes, San Francisco, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); G01N 33/5023 (2013.01); C12N 2710/16122 (2013.01); C12N 2710/16143 (2013.01); C12N 2740/15043 (2013.01); C12N 2830/00 (2013.01); C12N 2830/48 (2013.01); C12N 2830/60 (2013.01); C12N 2840/203 (2013.01);
Abstract
A recombinant expression vector comprising a nucleotide sequence encoding a herpesvirus transactivator, where the nucleotide sequence is operably linked to a herpesvirus control element is provided as are cell lines genetically modified to express a herpesvirus transactivator under the control of a herpesvirus control element. Also provided are methods of identifying agents that disrupt feedback regulation of a herpesvirus transcriptional control element by a herpesvirus transactivator.