The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 23, 2018

Filed:

Sep. 21, 2015
Applicants:

Universite DE Bourgogne, Dijon, FR;

Inra, Paris, FR;

Inserm, Paris, FR;

Inventors:

Fabrice Neiers, Pluvault, FR;

Renaud Seigneuric, Magny sur Tille, FR;

Loïc Briand, Saint Apollinaire, FR;

Carmen Garrido-Fleury, Talant, FR;

Assignees:

UNIVERSITE DE BOURGOGNE, Dijon, FR;

INRA, Paris, FR;

INSERM, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/02 (2006.01); C12N 15/72 (2006.01); C12N 15/74 (2006.01); C07K 14/47 (2006.01); C12N 9/12 (2006.01); C12P 21/00 (2006.01); C12N 1/20 (2006.01);
U.S. Cl.
CPC ...
C12N 15/72 (2013.01); C07K 14/47 (2013.01); C12N 1/20 (2013.01); C12N 9/1247 (2013.01); C12N 15/74 (2013.01); C12P 21/00 (2013.01); C12Y 207/07006 (2013.01);
Abstract

A method for the expression of a protein of interest by a bacterium, notable in that it comprises the culturing of a bacterium temporarily or continuously expressing an Hsp protein, in that said bacterium also comprises a nucleic acid sequence, encoding a protein of interest, under the control of a lac promoter and in that said bacterium is cultured in a medium which does not contain IPTG or a metabolized molecule in such a way as to automatically induce the induction of transcription from the lac promoter.


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