The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 23, 2018

Filed:

Jul. 18, 2014
Applicant:

Seoul National University R&db Foundation, Seoul, KR;

Inventors:

Yang-Sook Chun, Seoul, KR;

Hyoung Sook Park, Seoul, KR;

Jong-Wan Park, Seoul, KR;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/53 (2006.01); A61K 39/395 (2006.01); C07K 16/40 (2006.01); C12N 15/113 (2010.01); G01N 33/50 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1137 (2013.01); A61K 38/53 (2013.01); A61K 39/3955 (2013.01); C07K 16/40 (2013.01); C12N 15/113 (2013.01); G01N 33/5023 (2013.01); G01N 33/5044 (2013.01); G01N 33/5073 (2013.01); G01N 33/6875 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); G01N 2333/70567 (2013.01); G01N 2500/00 (2013.01);
Abstract

Provided is a method for suppressing an adipose differentiation comprising administering to a subject in need thereof a PPAR-v neddylation inhibitor for inhibiting adipocyte differentiation and a method for screening an adipocyte differentiation inhibitor using PPAR-v neddylation associated with adipocyte differentiation. The inhibitor of a neddylation pathway of PPAR-v inhibits the differentiation from mesenchymal stem cells to mast cells, and thus can be effectively used to treat obesity, and particularly, can be also useful in the treatment of severe obesity which cannot be excepted to be treated by existing obesity treatment agents.


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Chun, Yang-Sook. (2018). Methods for suppressing adipocyte differentiation (U.S. Patent No. 10106797). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10106797

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