The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 23, 2018
Filed:
Jun. 13, 2016
Applicant:
Novartis Ag, Basel, CH;
Inventors:
Joy Ghosh, Brookline, MA (US);
Mark Anthony Rutz, Munich, DE;
Kathrin Ulrike Tissot-Daguette, Neuried, DE;
Igor Splawski, Cambridge, MA (US);
Michael Roguska, Cambridge, MA (US);
Assignee:
NOVARTIS AG, Basel, CH;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 16/22 (2006.01); C07K 16/26 (2006.01); C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/26 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07K 16/22 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/21 (2013.01); C07K 2317/34 (2013.01); C07K 2317/55 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract
The present invention relates to compositions and methods for the inhibition of EPO. The invention provides antibodies and antigen binding fragments thereof that bind to EPO and are able to inhibit EPO-dependent cell proliferation and/or EPO-dependent cell signaling.