The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 23, 2018

Filed:

Aug. 04, 2015
Applicants:

Universität Regensburg, Regensburg, DE;

Friedrich-schiller-universität Jena, Jena, DE;

Universitätsklinikum Jena, Jena, DE;

Inventors:

Siavosh Mahboobi, Regensburg, DE;

Andreas Sellmer, Lappersdorf, DE;

Herwig Pongratz, Regensburg, DE;

Michel Leonhardt, Dachau, DE;

Oliver Krämer, Nackenheim, DE;

Frank-Dietmar Böhmer, Dornburg-Camburg, DE;

Gerhard Kelter, Ehrekirchen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/18 (2006.01); A61K 31/529 (2006.01); C07D 471/22 (2006.01); C07D 455/03 (2006.01); C07C 259/10 (2006.01); C07C 259/06 (2006.01); C07D 471/14 (2006.01);
U.S. Cl.
CPC ...
C07D 471/18 (2013.01); C07C 259/06 (2013.01); C07C 259/10 (2013.01); C07D 455/03 (2013.01); C07D 471/14 (2013.01); C07D 471/22 (2013.01);
Abstract

The present invention relates to small molecule compounds and their use as HDAC inhibitors and in the treatment of various diseases, such as cancer. The present invention further relates to methods of synthesizing the compounds and methods of treatment. H-L(HA), H is a head group selected from (head group 1), (head group 2), (head group 3), (head group 4), (head group 5) and (head group 6).


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