The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 23, 2018

Filed:

Oct. 06, 2015
Applicant:

Reviral Limited, Stevenage, GB;

Inventors:

Stuart Cockerill, Stevenage, GB;

Neil Mathews, Stevenage, GB;

Simon Ward, Sussex, GB;

Graham Lunn, Sussex, GB;

Michael Paradowski, Sussex, GB;

Jose Miguel Gascon Simorte, Sussex, GB;

Assignee:

REVIRAL LIMITED, Stevenage, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/10 (2006.01); C07D 403/06 (2006.01); C07D 401/06 (2006.01); A61K 31/416 (2006.01); A61K 31/4184 (2006.01); A61K 31/437 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
C07D 471/10 (2013.01); A61K 31/416 (2013.01); A61K 31/4184 (2013.01); A61K 31/437 (2013.01); C07D 401/06 (2013.01); C07D 403/06 (2013.01); C07D 405/14 (2013.01);
Abstract

Benzimidazoles of formula (I): wherein: one of X and Y is an N atom or a substituted C atom, and the other is CH; L is a single bond, Calkylene, Calkenylene or Calkynylene; Ris Calkyl, Calkenyl, Calkynyl, 3- to 10-membered cycloalkyl, 5- to 10-membered heterocyclyl or 5- to 12-membered heteroaryl, each of which is unsubstituted or substituted; Z is halo, Chaloalkyl, nitro, —CN, —N(R)2, —OR, —SR, —S(=0)R, or —S(=0)R; each Ris independently hydrogen, Calkyl, Calkenyl or C2-6 alkynyl, wherein said alkyl, alkenyl and alkynyl groups are unsubstituted or substituted; and m is 0 or 1; and the pharmaceutically acceptable salt thereof are inhibitors of RSV and can therefore be used to treat or prevent an RSV infection.


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