The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 23, 2018
Filed:
Oct. 20, 2014
Applicant:
Artax Biopharma Inc., Cambridge, MA (US);
Inventors:
Andrés Gagete Mateos, Cambridge, MA (US);
Julio Castro Palomino, Barcelona, ES;
Luc Marti Clauzel, Cambridge, MA (US);
Damiá Tormo Carulla, Cambridge, MA (US);
Assignee:
Artax Biopharma Inc., Cambridge, MA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 311/58 (2006.01); C07D 311/60 (2006.01); C07D 405/06 (2006.01); C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
C07D 311/58 (2013.01); C07D 311/60 (2013.01); C07D 405/06 (2013.01); C07D 405/12 (2013.01);
Abstract
The present invention relates to a group of compounds of formula (I) containing a chromene nucleus: and which present the ability to inhibit the lymphocytes proliferation mediated by the TCR interaction with Nck, so that the present invention also relates to the use of these compounds for the treatment of diseases or conditions wherein said interaction triggers a complication such as transplant rejection reactions, immune or autoimmune diseases, inflammatory diseases or proliferative diseases.