The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 23, 2018

Filed:

Aug. 04, 2016
Applicant:

Omeros Corporation, Seattle, WA (US);

Inventors:

Neil S. Cutshall, Snohomish, WA (US);

Jennifer Lynn Gage, Kenmore, WA (US);

Thomas Neil Wheeler, Raleigh, NC (US);

Thomas L. Little, Seattle, WA (US);

Assignee:

Omeros Corporation, Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/46 (2006.01); C07D 413/10 (2006.01); C07D 405/10 (2006.01); C07D 407/10 (2006.01); C07D 417/10 (2006.01);
U.S. Cl.
CPC ...
C07D 307/46 (2013.01); C07D 405/10 (2013.01); C07D 407/10 (2013.01); C07D 413/10 (2013.01); C07D 417/10 (2013.01);
Abstract

Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebral palsy, sleep disorders, pain, Tourette's syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. Pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs of the compounds are also provided. Also disclosed are compositions containing a compound in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting PDE10 in a warm-blooded animal in need of the same.


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