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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10106508 B1

PDFFull Text
Date of Patent:
Oct. 23, 2018

Filed:

Jan. 12, 2016

Quinazoline heterocyclic compound as egfr kinase inhibitor and preparation and application thereof

Applicant:

Beijing Scitech-mq Pharmaceuticals Limited, Beijing, CN;

Inventors:

Wang Sheng, Beijing, CN;

Leifu Yang, Beijing, CN;

Zhiyong Pan, Beijing, CN;

Assignee:

BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED, Beijing, CN;

Attorney:

Gokalp Bayramoglu

Primary Examiner:

Kahsay Habte

Int. Cl.
CPC ...
C07D 239/94 (2006.01); C07D 491/056 (2006.01); C07D 498/04 (2006.01); A61K 31/357 (2006.01); A61K 31/517 (2006.01); A61K 31/5375 (2006.01); A61K 39/395 (2006.01); C07D 405/14 (2006.01); A61P 35/02 (2006.01);
U.S. Cl.
CPC ...
C07D 239/94 (2013.01); A61K 31/357 (2013.01); A61K 31/517 (2013.01); A61K 31/5375 (2013.01); A61K 39/3955 (2013.01); A61P 35/02 (2018.01); C07D 405/14 (2013.01); C07D 491/056 (2013.01); C07D 498/04 (2013.01); A61K 2300/00 (2013.01);
Abstract

The present invention relates to an N-substituted-phenyl-5-substituted-alkoxy-2,3-dihydro-[1,4]dioxane[2,3-f]quinazolin-10-amine (I) or 4-substituted-arylamino-6-substituted-alkyl-6H-[1,4]oxazino[3,2-g]quinazoline-7(8H)-one (II) type compounds, a preparation method thereof and an application thereof as an inhibitor for epidermal growth factor receptor (EGFR) (comprising some mutant forms of EGFR) to treat cancer. These compounds and salts thereof can be used to treat or prevent various cancer diseases.

Find Patent Forward Citations

Sheng, Wang. (2018). Quinazoline heterocyclic compound as egfr kinase inhibitor and preparation and application thereof (U.S. Patent No. 10106508). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10106508

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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