The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 23, 2018
Filed:
Jul. 11, 2016
Applicant:
Vanderbilt University, Nashville, TN (US);
Inventors:
Craig L. Duvall, Nashville, TN (US);
Lawrence J. Marnett, Nashville, TN (US);
Jashim Uddin, Nashville, TN (US);
Thomas A. Werfel, Nashville, TN (US);
Mukesh Gupta, Nashville, TN (US);
Brenda C. Crews, Nashville, TN (US);
Assignee:
Vanderbilt University, Nashville, TN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); A61K 9/00 (2006.01); A61K 47/34 (2017.01); A61K 9/51 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0052 (2013.01); A61K 9/0019 (2013.01); A61K 9/5146 (2013.01); A61K 47/34 (2013.01); A61K 49/0041 (2013.01); A61K 49/0082 (2013.01);
Abstract
Disclosed are compositions that comprise a cyclooxygenase-2-selective therapeutic and/or diagnostic agent having a therapeutic and/or diagnostic agent conjugated to a NSAID drug; and a ROS-responsive nanoparticle. Methods of making and using these compositions for drug encapsulation and delivery are also disclosed.