The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 23, 2018

Filed:

Dec. 05, 2014
Applicants:

Inserm (Institut National DE LA Sante ET DE LA Recherche Medicale), Paris, FR;

Centre Hospitalier Universitaire DE Montpellier, Montpellier, FR;

Universite DE Montpellier, Montpellier, FR;

Inventors:

Christian Hamel, Montpellier, FR;

Vasiliki Kalatzis, Montpellier, FR;

Marie Pequignot, Montpellier, FR;

Nicolas Cereso, Montpellier, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 9/10 (2006.01); A61K 9/00 (2006.01); A61K 31/713 (2006.01); A61K 38/17 (2006.01); C12N 7/00 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 48/0058 (2013.01); A61K 9/0019 (2013.01); A61K 31/713 (2013.01); A61K 38/1709 (2013.01); A61K 48/005 (2013.01); A61K 48/0066 (2013.01); C12N 7/00 (2013.01); C12N 9/10 (2013.01); C12N 15/113 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01); C12N 2750/14132 (2013.01); C12N 2750/14141 (2013.01); C12N 2750/14143 (2013.01); C12N 2750/14171 (2013.01);
Abstract

The present invention relates to methods and pharmaceutical compositions for expressing a polynucleotide of interest in the retinal pigment epithelium of a subject. In particular, the present invention relates to a method for selectively expressing a polynucleotide of interest in the retinal pigment epithelium in an eye of a subject in need thereof comprising the step of transducing the retinal pigment epithelium with an amount of a rAAV2/5 vector containing the polynucleotide of interest.


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