The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 16, 2018

Filed:

Nov. 10, 2014
Applicant:

Purdue Research Foundation, West Lafayette, IN (US);

Inventors:

David D. Nolte, Lafayette, IN (US);

John J. Turek, West Lafayette, IN (US);

Kwan Jeong, Seoul, KR;

Assignee:

PURDUE RESEARCH FOUNDATION, West Lafayette, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01B 9/02 (2006.01); G03H 1/04 (2006.01); G03H 1/08 (2006.01); H01L 27/146 (2006.01);
U.S. Cl.
CPC ...
G01B 9/02091 (2013.01); G01B 9/02032 (2013.01); G01B 9/02082 (2013.01); G03H 1/0443 (2013.01); G03H 1/08 (2013.01); H01L 27/146 (2013.01); G03H 2001/045 (2013.01); G03H 2001/0445 (2013.01); G03H 2001/0467 (2013.01); G03H 2210/62 (2013.01); G03H 2222/33 (2013.01); G03H 2223/20 (2013.01);
Abstract

A system for motility contrast imaging a biological target within tissue comprising a CCD array; an illumination source for generating an incoming beam; a first beam splitter for receiving the incoming beam and producing an object beam and a reference beam; a second beam splitter for illuminating a multitude of biological targets with the object beam and for directing backscattered object beams towards the CCD array; a computer-controlled delay stage for zero-path-matching the reference beam to the backscattered object beams; a reference beam that intersects the backscattered object beams at an angle to produce a series of interference fringes that modulate Fourier-domain information; and a computer for receiving a time series of Fourier-domain information. The interference fringes between the backscattered object beam and the reference beam are recorded by the CCD array and passed to the computer which constructs a digital hologram at successive times.


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