The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 16, 2018

Filed:

Apr. 28, 2017
Applicants:

Hvidovre Hospital, Hvidovre, DK;

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Washington, DC (US);

Inventors:

Judith M. Gottwein, Frederiksberg C, DK;

Troels Kasper Hoyer Scheel, Copenhagen NV, DK;

Robert Purcell, Bethesda, MD (US);

Jens Bukh, Praestø, DK;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); C12Q 1/18 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/18 (2013.01); C12N 7/00 (2013.01); C12N 2770/24221 (2013.01);
Abstract

The present invention relates to molecular approaches to the production of nucleic acid sequences, which comprises the genome of infectious hepatitis C virus. In particular, the invention provides nucleic acid sequences which comprise the genomes of infectious hepatitis C viruses of either genotype 3a (strain S52) or genotype 4a (strain ED43). The invention therefore relates to the use of the nucleic acid sequences and polypeptides encoded by all or part of the sequences in the development of vaccines and diagnostic assays for HCV and in the development of screening assays for the identification of antiviral agents for HCV. The invention therefore also relates to the use of viral particles derived from laboratory animals infected with S52 and ED43 viruses.


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