The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 16, 2018
Filed:
Oct. 29, 2013
Applicants:
Agency for Science, Technology and Research, Singapore, SG;
National University of Singapore, Singapore, SG;
Inventors:
Assignee:
Agency for Science, Technology and Research, Singapore, SG;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/87 (2006.01); C12N 15/85 (2006.01); C12N 5/00 (2006.01); A61K 31/7084 (2006.01); A61K 48/00 (2006.01); A61K 31/711 (2006.01); A61K 47/34 (2017.01); A61K 9/127 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01); A61K 9/1272 (2013.01); A61K 31/711 (2013.01); A61K 39/0011 (2013.01); A61K 47/34 (2013.01); A61K 48/00 (2013.01); C12N 15/87 (2013.01); A61K 2039/5152 (2013.01); A61K 2039/5156 (2013.01); A61K 2039/55522 (2013.01);
Abstract
The present invention relates to a composition for transfecting a cell with a genetic material comprising a first agent capable of directing the genetic material away from the acidic compartments in the cell and a second agent capable of stabilizing the microtubule or a network thereof. The invention also relates to the use of the composition in the manufacture of a medicament for treating a disease, a method for delivering a genetic material into a cell and a kit.