The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 16, 2018

Filed:

Oct. 31, 2014
Applicant:

Kyoto University, Kyoto, JP;

Inventor:

Noriyuki Tsumaki, Kyoto, JP;

Assignee:

KYOTO UNIVERSITY, Kyoto, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/077 (2010.01); A61K 35/32 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0655 (2013.01); A61K 35/32 (2013.01); C12N 2500/25 (2013.01); C12N 2500/38 (2013.01); C12N 2501/115 (2013.01); C12N 2501/15 (2013.01); C12N 2501/155 (2013.01); C12N 2501/16 (2013.01); C12N 2501/19 (2013.01); C12N 2501/415 (2013.01); C12N 2506/45 (2013.01); C12N 2513/00 (2013.01); C12N 2533/54 (2013.01);
Abstract

Provided is a method for producing chondrocytes from pluripotent stem cells, the method comprising the steps of: (i) inducing pluripotent stem cells to differentiate into mesodermal cells in adherent culture, (ii) culturing the cells obtained by step (i) in adherent culture in a medium containing one or more substances selected from the group consisting of BMP2, TGFβ and GDF5, and (iii) culturing the cells obtained by step (ii) in suspension culture in a medium containing one or more substances selected from the group consisting of BMP2, TGFβ and GDF5. Also provided is a pharmaceutical product comprising the chondrocytes obtained by the method.


Find Patent Forward Citations

Tsumaki, Noriyuki. (2018). Efficient chondrocyte induction method (U.S. Patent No. 10100283). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10100283

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