The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 16, 2018
Filed:
Mar. 14, 2014
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Cory R. Nicholas, San Francisco, CA (US);
John L. Rubenstein, San Francisco, CA (US);
Arnold R. Kriegstein, Mill Valley, CA (US);
Arturo Alvarez-Buylla, Woodside, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/079 (2010.01); C12N 5/0793 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0618 (2013.01); C12N 5/0619 (2013.01); C12N 2500/90 (2013.01); C12N 2501/13 (2013.01); C12N 2501/41 (2013.01); C12N 2501/727 (2013.01); C12N 2501/999 (2013.01); C12N 2506/02 (2013.01); C12N 2506/45 (2013.01);
Abstract
Methods and systems for generating MGE precursor cells in vitro as well as compositions of enriched MGE precursor cells are provided. The methods and systems provide efficient production of MGE precursors. The methods and systems disclosed herein provide functional MGE precursors which differentiate into functional GABAergic interneurons.