The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 16, 2018
Filed:
Sep. 28, 2012
Applicant:
Era Biotech, S.a., Barcelona, ES;
Inventors:
Roser Pallisse Bergwerf, Valldoreix, ES;
Stefan Robert Schmidt, Laupheim, DE;
Didac Marco Feliu, Barcelona, ES;
Patricia Karina Carvajal Vallejos, Barcelona, ES;
Assignee:
ERA BIOTECH, S.A., Cerdanyola Del Vallès, Barcelona, ES;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 2/00 (2006.01); C12P 21/06 (2006.01);
U.S. Cl.
CPC ...
C07K 2/00 (2013.01); C12P 21/06 (2013.01);
Abstract
The present invention relates generally to robust split inteins. The split inteins described herein are active over a large temperature range, including temperatures as low as 0° C., over a wide pH range, and in the presence of chaotropic salts. The split inteins also show high tolerance to sequence variability in fused heterologous polypeptides and therefore are useful in protein purification and engineering techniques.